Lieven Lagae Selected Research

Intellectual Disability (Idiocy)

11/2023	Wearable detection of tonic seizures in childhood epilepsy: An exploratory cohort study.
7/2022	miRNAs and isomiRs: Serum-Based Biomarkers for the Development of Intellectual Disability and Autism Spectrum Disorder in Tuberous Sclerosis Complex.
1/2022	Down-regulation of the brain-specific cell-adhesion molecule contactin-3 in tuberous sclerosis complex during the early postnatal period.
1/2020	Prediction of Neurodevelopment in Infants With Tuberous Sclerosis Complex Using Early EEG Characteristics.
5/2017	Vagus Nerve Stimulation in children: A focus on intellectual disability.
1/2017	Coding and small non-coding transcriptional landscape of tuberous sclerosis complex cortical tubers: implications for pathophysiology and treatment.
3/2016	Early onset epileptic encephalopathy or genetically determined encephalopathy with early onset epilepsy? Lessons learned from TSC.

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Lieven Lagae Research Topics

Disease

43	Epilepsy (Aura) 11/2023 - 09/2005
35	Seizures (Absence Seizure) 11/2023 - 09/2007
20	Tuberous Sclerosis (Bourneville's Disease) 11/2023 - 10/2015
18	Myoclonic Epilepsies (Myoclonic Encephalopathy) 10/2023 - 07/2004
13	Drug Resistant Epilepsy 01/2022 - 09/2005
7	Intellectual Disability (Idiocy) 11/2023 - 03/2016
7	Inborn Genetic Diseases (Disease, Hereditary) 07/2022 - 01/2006
6	Lennox Gastaut Syndrome 11/2023 - 10/2014
5	Brain Diseases (Brain Disorder) 11/2023 - 03/2016
5	Autism Spectrum Disorder 07/2022 - 06/2019
5	Epileptic Syndromes 01/2020 - 07/2004
4	Sleepiness 10/2023 - 07/2015
4	Autistic Disorder (Autism) 01/2020 - 10/2002
3	Neoplasms (Cancer) 04/2024 - 03/2012
3	Fever (Fevers) 10/2023 - 07/2004
3	Sudden Unexpected Death in Epilepsy 01/2023 - 12/2021
3	Neurodevelopmental Disorders 10/2021 - 05/2017
3	Infantile Spasms (West Syndrome) 01/2021 - 09/2005
2	Reflex Epilepsy (Photosensitive Epilepsy) 08/2023 - 12/2019
2	Heart Valve Diseases (Valvular Heart Disease) 12/2019 - 10/2017
2	Status Epilepticus (Complex Partial Status Epilepticus) 12/2019 - 10/2014
2	Pulmonary Hypertension 10/2017 - 07/2012
2	Leukoencephalopathies 10/2016 - 05/2013
2	Dizziness (Lightheadedness) 01/2016 - 07/2015
1	Infertility (Sterility) 04/2024
1	Spasm (Spasms) 11/2023
1	Weight Gain 03/2023
1	Insulin Resistance 03/2023
1	Tuberculoma 03/2023
1	Febrile Seizures (Febrile Seizure) 01/2022
1	Measles 01/2022
1	Nevus (Nevi) 12/2021
1	Autoimmune Diseases of the Nervous System 01/2021
1	Progressive Myoclonic Epilepsies (Progressive Myoclonic Epilepsy) 01/2021
1	Cognitive Dysfunction 10/2020
1	Arnold-Chiari Malformation (Arnold-Chiari Syndrome) 09/2020
1	Congenital Abnormalities (Deformity) 01/2020
1	Pulmonary Arterial Hypertension 12/2019
1	Fatigue 12/2019
1	Lethargy 12/2019
1	Rare Diseases (Rare Disease) 12/2019

Drug/Important Bio-Agent (IBA)

20	trans-sodium crocetinate (crocetin)IBA 11/2023 - 10/2015
17	FenfluramineIBA 10/2023 - 07/2012
16	Anticonvulsants (Antiepileptic Drugs)IBA 09/2021 - 09/2007
6	Vigabatrin FDA Link 11/2023 - 09/2018
5	Biomarkers (Surrogate Marker)IBA 11/2023 - 04/2016
5	Valproic Acid (Depakote)FDA LinkGeneric 08/2023 - 07/2004
4	CannabidiolIBA 11/2023 - 01/2020
3	Everolimus FDA Link 11/2023 - 09/2018
3	Serotonin (5 Hydroxytryptamine)IBA 01/2023 - 05/2019
3	BenzodiazepinesIBA 01/2023 - 07/2004
3	Sodium Channels (Sodium Channel)IBA 12/2018 - 07/2004
3	perampanelIBA 01/2018 - 07/2015
2	stiripentolIBA 10/2023 - 07/2004
2	Oxcarbazepine (Trileptal)FDA LinkGeneric 01/2023 - 12/2020
2	Topiramate (Topamax)FDA LinkGeneric 01/2023 - 07/2004
2	Folic Acid (Vitamin M)FDA LinkGeneric 01/2023 - 01/2019
2	Mechanistic Target of Rapamycin Complex 1IBA 10/2021 - 01/2017
2	Proteins (Proteins, Gene)FDA Link 10/2020 - 05/2019
2	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 01/2020 - 06/2016
2	SolutionsIBA 10/2018 - 08/2015
2	Voltage-Gated Sodium ChannelsIBA 05/2017 - 06/2016
2	SodiumIBA 05/2017 - 07/2008
2	TOR Serine-Threonine KinasesIBA 03/2016 - 10/2015
2	Adrenocorticotropic Hormone (ACTH)FDA Link 12/2012 - 09/2005
1	SandIBA 11/2023
1	brivaracetamIBA 11/2023
1	Blood Glucose (Blood Sugar)IBA 10/2023
1	Levetiracetam (Keppra)FDA LinkGeneric 08/2023
1	Insulin-Like Growth Factor I (IGF-1)IBA 03/2023
1	Growth Hormone (Somatotropin)IBA 03/2023
1	Hormones (Hormone)IBA 03/2023
1	Aminobutyrates (Aminobutyric Acid)IBA 01/2023
1	Sigma-1 ReceptorIBA 01/2023
1	gamma-Aminobutyric Acid (GABA)IBA 01/2023
1	MicroRNAs (MicroRNA)IBA 07/2022
1	Cell Adhesion MoleculesIBA 01/2022
1	Serotonin ReceptorsIBA 01/2022
1	AntipyreticsIBA 01/2022
1	VaccinesIBA 01/2022
1	LigandsIBA 01/2022
1	NorfenfluramineIBA 09/2021
1	SuspensionsIBA 12/2020
1	Carbamazepine (Tegretol)FDA LinkGeneric 12/2020
1	CarbohydratesIBA 01/2020
1	valnoctamideIBA 12/2019
1	sec-butyl-propylacetamideIBA 12/2019

Therapy/Procedure

18	Therapeutics 03/2023 - 01/2012
7	Vagus Nerve Stimulation 05/2017 - 09/2007
3	Ketogenic Diet 01/2020 - 08/2009
2	Wearable Electronic Devices 11/2023 - 02/2022
2	Drug Substitution 02/2021 - 12/2008
2	Electrodes (Electrode) 01/2016 - 06/2013
2	Drug Therapy (Chemotherapy) 03/2012 - 05/2009
1	Radiotherapy 04/2024
1	Off-Label Use 01/2023
1	Dermabrasion 12/2021
1	Precision Medicine 02/2021
1	Treatment Delay 01/2021
1	Decompression 09/2020